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Using Roundup 0.7.8, this is still a problem for me.

The (edited by my) traceback I get is:

TypeError: argument 1 must be string or read-only buffer,
not instance
/usr/local/lib/python2.3/site-packages/roundup/backends/blobfiles.py
in storefile(self=<roundpsycopgsql 0x429c8b0c>,
classname='file', nodeid='3', property=None,
content=<ZPublisher.HTTPRequest.FileUpload instance>)
   85            
self.transactions.append((self.doStoreFile, (classname, nodeid,
   86                 property)))
   87         open(name, 'wb').write(content)
      global open = undefined, name =
'/roundup/simplistix/db/files/file/0/file3.tmp', global
write = undefined, content =
<ZPublisher.HTTPRequest.FileUpload instance>