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changing the module name is what i was thinking of.  i just
wanted to test it myself before suggesting.  unfortunately,
i do not have ready-to-use mod_python installation now...

going through roundup.instance really seems to be the right
thing.  Herman, you may try the following patch (untested):

--- mp_roundup.py.orig	2004-06-25 12:41:07.390625000 +0300
+++ mp_roundup.py	2004-06-29 10:40:31.437500000 +0300
@@ -23,9 +23,11 @@
 
 from mod_python import apache
 
+import roundup
+
 import config
 
-TRACKER = imp.load_package("mod_python_roundup_tracker",
config.TRACKER_HOME)
+TRACKER = roundup.instance.open(config.TRACKER_HOME)
 
 class Headers(dict):
 

another possible solution is specifying another
PythonInterpreter for the second tracker.